My husband & I have both benefited greatly from taking CoQ10, he has cardiomyopathy (takes 1 softgel with 1000 mg L-Carnitine/2 x per day), I have early angina (take 1 softgel/day w/ 500 mg L-Carnitine). I haven't experienced angina since starting on this regimen over a year ago, and have much improved energy. My husband's heart health has improved!! Everyone over 50 or taking a statin drug should take CoQ10. Statins deplete the body of this co-enzyme, which, along with L-Carnitine, is essential to cardiovascular health.